The European electronic health record exchange format (EEHRxF) allows citizens to quickly access and share their health data with healthcare professionals within the EU. The EU-funded XpanDH project will build capacity in individuals and organisations with the aim of creating, adapting and exploring the use of interoperable digital health solutions through a shared adoption of the EEHRxF across the EU. The project will develop robust technical specifications and resources for the EEHRxF building; establish the X-Bundle Readiness model and verify its usefulness in the real world; mature a pan-European digital health ecosystem for solution providers and end users; and develop a framework for a sustainable health ecosystem.