Women treated with supradiaphragmatic radiotherapy (SRT) for Hodgkin Lymphoma (HL) at an early age have an increased risk of developing breast cancer.
5,002 women who had HL treatment between 1956 and 2003 were questioned as part of a recall to offer counselling to women about breast cancer risks. Follow up continued until 2012.
The data analysis showed that women given SRT for HL close to when they had their first period had a significant risk of developing breast cancer. Greater surveillance was offered to this group to screen for early breast cancer. The administration of medication that delayed puberty was also considered.
Cancer registries were used to identify participants. Breast Cancer Now and The European Commission supported this research.
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